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Research Grade Astegolimab

Catalog #:   DHF88301 Specific References (0) DATASHEET
Host species: Human
Isotype: IgG2-kappa
Applications: Research Grade Biosimilar
Expression system: Mammalian Cells
Overview

Catalog No.

DHF88301

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Human

Isotype

IgG2-kappa

Clonality

Monoclonal

Applications

Research Grade Biosimilar

Target

T1, DER4, Interleukin-1 receptor-like 1, ST2, IL1RL1, Protein ST2

Concentration

0.91 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q01638

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

AMG-282, MSTT-1041A, RG-6149, RO-7187807, CAS: 2173054-79-8

Clone ID

Astegolimab

Note

For research use only. Not suitable for clinical or therapeutic use.

Data Image
  • Bioactivity
    Detects Human IL1RL1/ST2 in indirect ELISAs.
  • SDS-PAGE
    SDS PAGE for Astegolimab
  • SEC-HPLC
    The purity of this product is >95% as determined by SEC-HPLC.
  • Bioactivity
    Fig. 1 EA treatment reduces cerebral infarct volume after MCAO/R Fig. 2 EA treatment improves cognitive function after MCAO/R.
    Data sourced from citation (PMID: 40801996)
  • Bioactivity
    Fig. 3 EA treatment improves the integrity of myelin sheath structure after MCAO/R via the IL-33/ST2 pathway. Fig. 4 EA treatment promotes the proliferation of oligodendrocyte precursor cells (OPCs) and oligodendrocytes after MCAO/R.
    Data sourced from citation (PMID: 40801996)
  • Bioactivity
    Fig. 6 EA treatment reduces the expression of pro-inflammatory factors and increases the expression of anti-inflammatory factors.
    Data sourced from citation (PMID: 40801996)
References
Datasheet

Document Download

Research Grade Astegolimab.pdf

 

$ 530
Product specifications
1 mg 530 5 mg 1590 25 mg 4130

Contact Information

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Distributor list

For research use only. Not for human or drug use.

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Research Grade Astegolimab [DHF88301]
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